CoronaVirus - Possible Vaccines and Treatments

Discussion in 'COVID-19' started by paulF, 25th Mar, 2020.

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  1. Shazz@

    Shazz@ Well-Known Member

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  2. random

    random Well-Known Member

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    l'm surprised there's nothing here about the vac Australia is trialing for wait for it , the US , of course.
    Why does this smell of well , just yet more aussie US brownosing , maybe we were the only suckers dumb enough and why aren't they trialing it themselves , or the UK or Europe .
    There was some dribble about it was because our medical teams were so good , yeah l'll bet , bit of flattery done the job l'm sure there are many better in many countries not to mention in the US .
     
  3. Shazz@

    Shazz@ Well-Known Member

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    You mean this?
    Maybe read the through the thread and not make assumptions.
     
    Last edited: 26th May, 2020
  4. random

    random Well-Known Member

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    Ahh , this thread is how many pages , yeah right . No , just going on the report l saw that is pretty well how they told it and how it appeared to me too just going on what they went into.
    However , l'd be more than pleased if it isn't as it seemed.
    ps , Just read the link , still doesn't explain why us , like there wouldn't be 100 others just as good.
     
    Last edited: 26th May, 2020
  5. geoffw

    geoffw Moderator Staff Member

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    However, there have been questions raised about this study
    Questions raised over hydroxychloroquine study which caused WHO to halt trials for Covid-19
    This is a part of the normal scientific review process of published papers, a process which helps to validate or invalidate published data. In this case, there has just been a signal that some of the data doesn't add up, so results should be treated with caution until validated or disproven.

    I'll repeat my precious statement - hydroxychloroquine still hasn't been given a red light or a green light, and so regardless of what researchers may find about the efficacy of this drug or its cousin chloroquine, it was irresponsible for an unproven drug to be promoted by a prominent layman as a treatment.
     
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  6. geoffw

    geoffw Moderator Staff Member

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    Warm Weather Won’t Stop the Spread of COVID-19

    However, a slightly different view
    Does warmer weather slow coronavirus?
    Climate may have some role in slowing the spread of Covid-19, but it's unlikely to stop it. The slowing may be due to humidity, UV light, or having people spend more time indoors close together in cold weather.
     
  7. Lizzie

    Lizzie Well-Known Member

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    It's been shown that higher vit D in the system makes one more resistant ... so it may not be that the weather is warmer but simply that we get more sunlight
     
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  8. geoffw

    geoffw Moderator Staff Member

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    That may be one factor as well - but being a biological system in a complex world, no single factor is likely to the only thing which influences its spread.
     
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  9. Shazz@

    Shazz@ Well-Known Member

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    Though they do say “In reviewing the data from each of the hospitals in the registry, we noted that this hospital had a nearly 100% composition of Asian race and a relatively high use of chloroquine compared to non-use in Australia. This hospital should have more appropriately been assigned to the Asian continental designation.

    He said the error did not change the overall study findings. It did mean that the Australian data in the paper would be revised to four hospitals and 63 deaths,.”

    Agree with you that we still don’t know enough about the drug. COVID-Shield study is about prevention, not treatment. Would be interested to see what they do about the ASCOT study, which is treatment.
     
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  10. Casteller

    Casteller Well-Known Member

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    Another major effect of temperature is the survival of the virus on surfaces, in the right conditions it can last days, in warm weather hours, in direct sunlight minutes.

    Spain's numbers inched down for weeks while everyone was in quarantine, then about 3 weeks ago the hot weather arrived (and people were allowed outside for the first time, good timing) , and two weeks after that new cases plummeted. See what happens now that everyone is allowed out again, few hundred kids in the park playing yesterday and plenty of groups of people outside now when allowed. From next week phase two and quarantine timing scrapped.

    So climate, masks, distancing, virus burnout (a few million have already had it in Spain) probably all make a difference, but perhaps total quarantining of the population actually makes things worse by suppressing the immune system of many people.
     
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  11. Shazz@

    Shazz@ Well-Known Member

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    Hard to compare the 2 studies. The first one is a proper trial. There’s no details on the second trial.
     
  12. random

    random Well-Known Member

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    Personally l'd think summer would be a no brainer but l heard one of the specialists say too that sunshine kills virus's and a virus also doesn't live on surfaces very long in sunshine either.
     
  13. SatayKing

    SatayKing Well-Known Member

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  14. Lacrim

    Lacrim Well-Known Member

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    Don't forget drinking disinfectant kills it as well ;)
     
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  15. Lacrim

    Lacrim Well-Known Member

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    I think its more that in a lockdown you are thrust right up against the virus all day/all night if someone in your household has it.
     
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  16. Lizzie

    Lizzie Well-Known Member

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    Very true - but also being a biological system in a complex world - one missing key factor, amongst thousand of other factors, can screw the whole system up

    But yes - masks, sunshine, distancing - it all helps
     
  17. geoffw

    geoffw Moderator Staff Member

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    While this isn't actually a treatment or cure, the fact that there is an increased susceptibility to covid-19 for people with a certain gene variant (which also makes people more susceptible to dementia) may help to determine how it does its damage.
    Dementia gene raises risk of severe COVID-19
     
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  18. Lacrim

    Lacrim Well-Known Member

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    Alright that's it! Give me the damn vaccine...NOW!
     
  19. Shazz@

    Shazz@ Well-Known Member

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    More questions raised on this study.
    Covid-19 study on hydroxychloroquine use questioned by 120 researchers and medical professionals

    Usually observational studies/real world studies (phase 4) are done after the phase 3 studies. In these unprecedented times during a pandemic, there was a need to do the reverse, but this raises the limitations of these types of studies.
     
  20. Shazz@

    Shazz@ Well-Known Member

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    Unfortunately, not many people understand this. It doesn’t help that most of the media reports out there interview scientists who talk about these swift timelines, and have no idea about the regulatory requirements or logistical issues. I don’t doubt they believe they can develop a vaccine quickly (there is millions of dollars being poured into this and there is a lot of public interest in this outcome). But there is a big difference on producing a vaccine, versus having a vaccine that is commercially available to the public.
     
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